Peer-Reviewed Journal Publications:
Scientific Publications
2023
Chromosomal, Gestational, and Neonatal Outcomes of Embryos Classified as Mosaic by Preimplantation Genetic Testing for Aneuploidy
Fertility and Sterility, 2023. https://doi.org/10.1016/j.fertnstert.2023.07.022
2022
SARS-CoV-2 Can Infect Human Embryos
Scientific Reports, 2022. https://www.nature.com/articles/s41598-022-18906-1
2021
Haplotype-Aware Inference Of Human Chromosome Abnormalities
PNAS, 2021. https://www.pnas.org/content/118/46/e2109307118
Using Outcome Data From One Thousand Mosaic Embryo Transfers To Formulate An Embryo Ranking System For Clinical Use
Fertility and Sterility, 2021. https://www.fertstert.org/article/S0015-0282(20)32716-3/fulltext
Let The Data Do The Talking: The Need To Consider Mosaicism During Embryo Selection
Fertility and Sterility, 2021. https://doi.org/10.1016/j.fertnstert.2021.09.008
2020
Preimplantation Genetic Testing For Chromosomal Abnormalities: Aneuploidy, Mosaicism, And Structural Rearrangements
Genes, 2020. https://www.mdpi.com/2073-4425/11/6/602
2019
Estimating Demand For Germline Genome Editing: An In Vitro Fertilization Clinic Perspective
The CRISPR Journal, 2019. https://www.liebertpub.com/doi/abs/10.1089/crispr.2019.0044
Births From Embryos With Highly Elevated Levels Of Mitochondrial DNA
Reproductive Biomedicine Online, 2019. https://www.rbmojournal.com/article/S1472-6483(19)30373-6/abstract
One Hundred Mosaic Embryos Transferred Prospectively In A Single Clinic: Exploring When And Why They Result In Healthy Pregnancies
Fertility and Sterility, 2019. https://www.fertstert.org/article/S0015-0282(18)32141-1/fulltext
Assessment Of Aneuploidy Concordance Between Clinical Trophectoderm Biopsy And Blastocyst
Human Reproduction, 2019. https://doi.org/10.1093/humrep/dey327
2017
Is MtDNA Quantitation Of Trophectoderm Cells Predictive Of Blastocyst Development Competence And Outcome In Clinical IVF?
Journal of Assisted Reproductive Medicine, 2017. https://link.springer.com/article/10.1007%2Fs10815-017-1072-6
Accurate Quantitation Of Mitochondrial DNA Reveals Uniform Levels In Human Blastocysts Irrespective Of Ploidy, Age, Or Implantation Potential.
Fertility and Sterility, 2017. Selected as a ‘Seminal Contribution’. http://www.fertstert.org/article/S0015-0282(16)62848-0/fulltext
Commentary by Dr. Richard Scott: http://www.fertstert.org/article/S0015-0282(16)63024-8/fulltext
Video highlight of the study: https://youtu.be/ELBnPMZaX5E
Abstract Publications and Presentations:
2023
Mosaicism Detected By Routine Clinical PGT-A Persisting Through Pregnancy: Incidence, Implication, and Outcome
Preimplantation Genetic Diagnosis International Society (PGDIS), Paris, France 2023
Clinical Interpretation Of Mosaicism, Its Incidence And Reproductive Potential
Preimplantation Genetic Diagnosis International Society (PGDIS), Paris, France 2023
Ranking System For Mosaic Embryos
Pacific Coast Reproductive Society (PCRS), Indian Wells, CA 2023
2022
SARS-CoV-2 Y Desarollo Embrionario
Red Latinoamericana de Reproduccion Asistida (REDLARA), Panama City, Panama 2022
Que Nos Dicen Las Nuevas Tecnologias Sobre El Mosaicismo?
Red Latinoamericana de Reproduccion Asistida (REDLARA), Panama City, Panama 2022
Update On The International Registry Of Mosaic Embryo Transfers
American Society of Reproductive Medicine (ASRM), Anaheim, CA 2022
Is It Safe To Transfer Mosaic Embryos?
Canadian Fertility and Andrology Society (CFAS), Halifax, Canada 2022
Human Embryo Vulnerability To SARS-CoV-2 Infection: What Are The Risks?
Canadian Fertility and Andrology Society (CFAS), Halifax, Canada 2022
Prenatal Outcomes Of Mosaic Embryo Transfer And Neonatal Assessment
European Society of Human Reproduction and Embryology (ESHRE), Milan, Italy 2022
Vulnerability Of Human Preimplantation Embryos To SARS-CoV-2 Infection
European Society of Human Reproduction and Embryology (ESHRE), Milan, Italy 2022
Follow-Up Of Embryos With Mosaicism And Segmental Aneuploidy
Preimplantation Genetic Diagnosis International Society (PGDIS), Berlin, Germany 2022
2021
Making Sense Of Mosaicism In PGT-A
World Congress on Controversies in Preconception, Preimplantation and Prenatal Genetic Diagnosis (CoGEN), Online, 2021
Assessing The Embryo’s DNA For Aneuploidy
Howard and Georgeanna Jones Symposium on Assisted Reproductive Technology
American Society of Reproductive Medicine (ASRM), Baltimore, USA 2021
The Embryo As A Source Of Diagnostic Material
American Society of Reproductive Medicine (ASRM), Baltimore, USA 2021
The Effect Of Culturing Conditions And Embryo Morphology On The Performance Of Non-Invasive PGT-A
American Society of Reproductive Medicine (ASRM), Baltimore, USA
Presented By Our Collaborators
Embryo Mosaicism – Reproductive Outcome
Preimplantation Genetic Diagnosis International Society (PGDIS) Live Webinar, June 2021
See the recorded webinar here.
Obstetric Outcomes Of Mosaic Embryo Transfers
Canadian Fertility & Andrology Society (CFAS) Webinar, June 2021
Selecting The Best Mosaic Embryo For Transfer
International IVF Initiative (I3) Webinar, January 2021
See the recorded webinar here.
2020
Human Pre-Implantation Embryos Are Permissive to SARS-CoV-2 Entry (Late-Breaking Abstract)
American Society of Reproductive Medicine (ASRM), Virtual Meeting, 2020 See full abstract
New Insights From One Thousand Mosaic Embryo Transfers: Features of Mosaicism Dictating Rates of Implantation, Spontaneous Abortion, and Neonate Health (Prize Paper Session)
American Society of Reproductive Medicine (ASRM), Virtual Meeting, 2020 See full abstract
Assessment Of Cell-Free DNA From Embryo Spent Media And Its Effect On Non-Invasive PGT-A Concordance To Conventional PGT-A And Calculated Copy Number Noise
American Society of Reproductive Medicine (ASRM), Virtual Meeting, 2020 See full abstract
Presented By Our Collaborators
RNA For PGT-A And Identification Of New Biomarkers Of Clinical Outcome In IVF
American Society of Reproductive Medicine (ASRM), Virtual Meeting, 2020 See full abstract
Presented By Our Collaborators
2019
Blastocysts With Disproportionally High Mitochondrial DNA Copy Number Can Result In Healthy Babies
The Foundation for Reproductive Medicine (FRM), New York, USA 2019 See full abstract
Mosaic Embryos – A Comprehensive And Powered Analysis Of their Clinical Outcomes
American Society of Reproductive Medicine (ASRM), Philadelphia, USA 2019 See abstract here
Mosaic Embryo Transfers – A Compiled Analysis Of Published Data
Preimplantation Genetic Diagnosis International Society (PGDIS), Geneva, Switzerland 2019 See full abstract
CRISPR Gene Editing And Ramifications (Keynote Address)
Hamilton Thorne Clinical Manipulation Workshop, Fort Lauderdale, USA 2019 See Program
2018
100 Mosaic Embryo Transfers In A Single Clinic: What We Have Learned
American Society of Reproductive Medicine (ASRM), Denver, USA 2018 See full abstract
80 Mosaic Embryo Transfers In A Single Clinic With In-House PGT-A: What We Have Learned
Preimplantation Genetic Diagnosis International Society (PGDIS), Bangkok, Thailand 2018 See full abstract
Aneuploidy Concordance Between Trophectoderm And Inner Cell Mass By Next-Generation Sequencing In 100 Blastocysts
Preimplantation Genetic Diagnosis International Society (PGDIS), Bangkok, Thailand 2018 See full abstract
Blastocysts With Disproportionally High MtDNA Copy Number Can Result In Healthy Babies
Preimplantation Genetic Diagnosis International Society (PGDIS), Bangkok, Thailand 2018 See full abstract
Assessment Of Aneuploidy Concordance Between Trophectoderm And Inner Cell Mass In 100 Blastocysts By Next-Generation Sequencing
Biomarker Meeting in Personalized Reproductive Medicine, Valencia, Spain 2018 See full abstract
2017
Exploring The Chromosomal Concordance Between Trophectoderm And Inner Cell Mass Reveals A 6% ‘Biological False Negative’ Rate During Preimplantation Genetic Screening
American Society of Reproductive Medicine (ASRM), San Antonio, USA 2017 See full abstract
Quantifying Mitochondrial DNA To Predict Implantation: Myth Or Reality?
Cambridge Healthtech Institute’s Advances in Reproductive Genetic Diagnostics, Boston, USA 2017 See full abstract
Aneuploidy Concordance Between Trophectoderm And Inner Cell Mass By Next-Generation Sequencing
Cambridge Healthtech Institute’s Advances in Reproductive Genetic Diagnostics, Boston, USA 2017 See full abstract
Validating PGS By Probing The Karyotypic Concordance Between ICM And TE
Preimplantation Genetic Diagnosis International Society (PGDIS), Valencia, Spain 2017 See full abstract
The Effects Of Laser Manipulation On Biopsy Karyotype In PGS
Preimplantation Genetic Diagnosis International Society (PGDIS), Valencia, Spain 2017 See full abstract
Mitochondrial DNA As A Marker For Ploidy And Implantation In IVF
Fertility and Sterility Journal Club Global, January 2017
2016
Correction Factor Reveals Uniform Levels Of Mitochondrial DNA In Human Blastocysts Irrespective Of Ploidy, Age, Or Implantation Potential
American Society of Reproductive Medicine (ASRM), Salt Lake City, USA 2016 See full abstract
Mathematical Correction Method To Accurately Determine Mitochondrial DNA Levels Reveals Uniformity In Blastocysts
Preimplantation Genetic Diagnosis International Society (PGDIS), Bologna, Italy 2016 See full abstract
