Articles

PEER REVIEWED JOURNAL PUBLICATIONS:

 

Preimplantation Genetic Testing for Chromosomal Abnormalities: Aneuploidy, Mosaicism, and Structural Rearrangements

Genes, 2020. https://www.mdpi.com/2073-4425/11/6/602/htm

 

Estimating Demand for Germline Genome Editing: An In Vitro Fertilization Clinic Perspective

The CRISPR Journal, 2019. https://www.liebertpub.com/doi/abs/10.1089/crispr.2019.0044

 

Births From Embryos With Highly Elevated Levels Of Mitochondrial DNA

Reproductive Biomedicine Online, 2019. https://www.rbmojournal.com/article/S1472-6483(19)30373-6/abstract

 

One  Hundred Mosaic Embryos Transferred Prospectively In A Single Clinic:  Exploring When And Why They Result In Healthy Pregnancies

Fertility and Sterility, 2019.   https://www.fertstert.org/article/S0015-0282(18)32141-1/fulltext

Among the 10 Most Cited Articles in the Journal Fertility and Sterility in 2019. 

 

Assessment of aneuploidy concordance between clinical trophectoderm biopsy and blastocyst

Human Reproduction, 2019.   https://doi.org/10.1093/humrep/dey327

 

Is MtDNA Quantitation of Trophectoderm Cells Predictive of Blastocyst Development Competence and Outcome in Clinical IVF?

Journal of Assisted Reproductive Medicine, 2017.  https://link.springer.com/article/10.1007%2Fs10815-017-1072-6

 

Accurate Quantitation of Mitochondrial DNA Reveals Uniform Levels in Human Blastocysts Irrespective of Ploidy, Age, or Implantation Potential.

Fertility and Sterility, 2017. Selected as Seminal Contribution.  http://www.fertstert.org/article/S0015-0282(16)62848-0/fulltext          

Commentary by Dr. Richard Scott:   http://www.fertstert.org/article/S0015-0282(16)63024-8/fulltext

Among the 25 Most Cited Articles in the Journal Fertility and Sterility Since 2017.  https://www.journals.elsevier.com/fertility-and-sterility/most-cited-articles

 

CONFERENCE ABSTRACTS AND PRESENTATIONS:

 

Human Pre-Implantation Embryos Are Permissive to SARS-CoV-2 Entry

American Society of Reproductive Medicine (ASRM), Virtual Conference 2020. Late Breaking Abstract Session.

 

New Insights From One Thousand Mosaic Embryo Transfers: Features of Mosaicism Dictating Rates of Implantation, Spontaneous Abortion, and Neonate Health

American Society of Reproductive Medicine (ASRM), Virtual Conference 2020. Prize Paper Session.

 

Assessment of cell-free DNA concentration and fragmentation from embryo spent media and its effect on non-invasive PGT-A concordance to conventional PGT-A and calculated copy number noise

American Society of Reproductive Medicine (ASRM), Virtual Conference 2020. (Presented by our collaborator Jacob Meyers)

 

RNA for PGT-A and Identification of New Biomarkers of Clinical Outcome in IVF

American Society of Reproductive Medicine (ASRM), Virtual Conference 2020. (Presented by our collaborator Julie Laliberte)

 

New evidence on mosaic developmental potential: multicentric study of 822 mosaic embryos diagnosed by preimplantation genetic testing with trophectoderm biopsy

Preimplantation Genetic Diagnosis International Society (ESHRE), Virtual Conference 2020. (Presented by our collaborator Francesca Spinella)

 

Blastocysts with disproportionally high mitochondrial DNA copy number can result in healthy babies

FRM Conference, New York, NY, USA 2019

 

Mosaic Embryos – A Comprehensive and Powered Analysis of their Clinical Outcomes

American Society of Reproductive Medicine (ASRM), Philadelphia, PA, USA 2019

 

Mosaic Embryo Transfers – A Compiled Analysis of Published Data

Preimplantation Genetic Diagnosis International Society (PGDIS), Geneva, Switzerland 2018.

 

Novel approach enables the simultaneous detection of SNV and CNV for PGT-M/T using a single-tube assay

Preimplantation Genetic Diagnosis International Society (PGDIS), Geneva, Switzerland 2018. (Presented by our collaborator Andrew Farmer)

 

100 Mosaic Embryo Transfers in a Single Clinic: What We Have Learned

American Society of Reproductive Medicine (ASRM), Denver, CO, USA 2018

 

Aneuploidy concordance between trophectoderm and inner cell mass by next-generation sequencing

Northern California Association of Reproductive Biologists (NCARB), San Francisco, CA, USA 2018

 

80 mosaic embryo transfers in a single clinic with in-house PGT-A: What we have learned

Preimplantation Genetic Diagnosis International Society (PGDIS), Bangkok, Thailand 2018

 

Aneuploidy concordance between trophectoderm and inner cell mass by next-generation sequencing in 100 blastocysts

Preimplantation Genetic Diagnosis International Society (PGDIS), Bangkok, Thailand 2018

 

Blastocysts with disproportionally high mtDNA copy number can result in healthy babies

Preimplantation Genetic Diagnosis International Society (PGDIS), Bangkok, Thailand 2018   

 

Assessment of aneuploidy concordance between trophectoderm and inner cell mass in 100 blastocysts by next-generation sequencing

Biomarker Meeting in Personalized Reproductive Medicine, Valencia, Spain 2018     

 

CRISPR in Human Embryos: An IVF Clinic’s Perspective

Keystone Symposium: Precision Genome Editing with Programmable Nucleases, Keystone, CO, USA 2018

 

Exploring the Chromosomal Concordance Between Trophectoderm and Inner Cell Mass Reveals a 6% ‘Biological False Negative’ Rate During Preimplantation Genetic Screening

American Society of Reproductive Medicine (ASRM), San Antonio, TX, USA 2017  

 

Quantifying Mitochondrial DNA to Predict Implantation: Myth or Reality?

Cambridge Healthtech Institute’s Advances in Reproductive Genetic Diagnostics, Boston,  USA 2017 

 

Aneuploidy concordance between trophectoderm and inner cell mass by next-generation sequencing

Cambridge Healthtech Institute’s Advances in Reproductive Genetic Diagnostics, Boston,  USA 2017   

 

Validating PGS by Probing the Karyotypic Concordance Between ICM and TE

Preimplantation Genetic Diagnosis International Society (PGDIS), Valencia, Spain 2017 

 

The Effects of Laser Manipulation on Biopsy Karyotype in PGS

Preimplantation Genetic Diagnosis International Society (PGDIS), Valencia, Spain 2017  

 

Mitochondrial DNA as a Marker for Ploidy and Implantation in IVF

Fertility and Sterility Journal Club Global, January 2017

 

Correction Factor Reveals Uniform Levels of Mitochondrial DNA in Human Blastocysts Irrespective of Ploidy, Age, or Implantation Potential                      

American Society of Reproductive Medicine (ASRM), Salt Lake City, USA 2016   

 

Mathematical Correction Method to Accurately Determine Mitochondrial DNA Levels Reveals Uniformity in Blastocysts

Preimplantation Genetic Diagnosis International Society (PGDIS), Bologna, Italy 2016  

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